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Gonadotropins and leptin : the role and molecular mechanism in normal and neoplastic ovarian epithelium cells

https://libraries.phsa.ca/permalink/catalog113965

http://hdl.handle.net/2429/18509

Choi, Jung-Hye. Vancouver, BC: University of British Columbia , 2006. (Thesis) — 1 copy, 1 available
Audience
Professional
Agency
BC Children's and Women's
Location
Study & Learning Commons
Call Number
Thesis Shelf
Ovarian cancer is the sixth most common cancer and the fifth leading cause of cancer-related death among women in developed countries. There is increasing evidence suggesting that the hormonal environment of the normal ovarian surface epithelium (OSE) and ovarian epithelial cancer (OEC) cells is as…
Title
Gonadotropins and leptin : the role and molecular mechanism in normal and neoplastic ovarian epithelium cells
Author
Choi, Jung-Hye
Place
Vancouver, BC
Publisher
University of British Columbia
Year Published
2006
Topics
Faculty of Medicine
Theses
Abstract
Ovarian cancer is the sixth most common cancer and the fifth leading cause of cancer-related death among women in developed countries. There is increasing evidence suggesting that the hormonal environment of the normal ovarian surface epithelium (OSE) and ovarian epithelial cancer (OEC) cells is associated with the development and progression of ovarian cancer. Exposure to excess gonadotropins and leptin, related to menopause or infertility therapy and obesity, respectively, has been implicated as a risk factor for ovarian cancer.
Language
English
Material Type
Thesis
Agency
BC Children's and Women's
Location
Study & Learning Commons
URL
http://hdl.handle.net/2429/18509
Audience
Professional
Call Number
Thesis Shelf
Copy 1 BC Children's and Women's Study & Learning Commons Thesis Shelf Available

Influences of endocrine and autocrine factors in normal and neoplastic ovarian surface epithelium

https://libraries.phsa.ca/permalink/catalog113974

http://hdl.handle.net/2429/13688

Choi, Kyung-Chul. Vancouver, BC: University of British Columbia , 2001. (Thesis) — 2 copies, 2 available
Audience
Professional
Agency
BC Children's and Women's
Location
Study & Learning Commons
Call Number
Thesis Shelf
The common epithelial ovarian tumors appear to arise from the ovarian surface epithelium (OSE), which is a simple squamous-to-cuboidal meso^helium covering the ovary. The exact mechanism of ovarian tumorigenesis is not well known even though this disease is the most frequent cause of cancer death i…
Title
Influences of endocrine and autocrine factors in normal and neoplastic ovarian surface epithelium
Author
Choi, Kyung-Chul
Place
Vancouver, BC
Publisher
University of British Columbia
Year Published
2001
Topics
Faculty of Medicine
Theses
Abstract
The common epithelial ovarian tumors appear to arise from the ovarian surface epithelium (OSE), which is a simple squamous-to-cuboidal meso^helium covering the ovary. The exact mechanism of ovarian tumorigenesis is not well known even though this disease is the most frequent cause of cancer death in gynecological malignancies. Repeated ovulation contributes to neoplastic transformation of OSE, indicating that the process of healing ruptured OSE may contribute to the disease. Therefore, it has been hypothesized that endocrine and autocrine factors may influence the occurrence of ovarian tumors in women.
Language
English
Material Type
Thesis
Agency
BC Children's and Women's
Location
Study & Learning Commons
URL
http://hdl.handle.net/2429/13688
Audience
Professional
Call Number
Thesis Shelf
Copy 1 BC Children's and Women's Study & Learning Commons Thesis Shelf Available
Copy 2 BC Children's and Women's Study & Learning Commons Thesis Shelf Available