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Homeobox genes, which code for families of transcription factors, act at the top of genetic hierarchies. HOX genes specify positional identity during development, and in adult tissues, regulate differentiation and proliferation. Most ovarian carcinomas are derived from the ovarian surface epitheliu…
Loss of BRCA1/BRCA2 function through genetic or epigenetic mechanisms is common in epithelial ovarian carcinomas (EOC), but because there are multiple potential mechanisms of loss, the overall frequency is unknown. We characterized loss of BRCA1/BRCA2 at the DNA, RNA and protein level from an unsel…
Condensed proceedings of an International Symposium held on 25th May 1982 at the Royal College of Obstetricians and Gynaecologists, Regents Park, London
Provides basic consumer health information on risk factors, prevention, symptoms, diagnosis, and treatment of various types of breast cancer, along with facts about coping during and after treatment. Includes index, glossary of related terms and directory of resources. ; Table of contents: ; Part I…