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    Investigation of confined placental mosaicism and aberrant H19/ IGF2 imprinting in pregnancies conceived by in-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI)

    https://libraries.phsa.ca/permalink/catalog113955

    http://hdl.handle.net/2429/33832

    Chan Wong, Edgar Antonio. Vancouver, BC: University of British Columbia , 2011. (Thesis) — 1 copy, 1 available
    Audience
    Professional
    Agency
    BC Children's and Women's
    Location
    Study & Learning Commons
    Call Number
    Thesis Shelf
    In-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are two of the most common forms of assisted reproductive technologies (ARTs) used to treat human infertility. Presently, over two million children have been conceived by ART. The majority of these children are born healthy. H…
    Title
    Investigation of confined placental mosaicism and aberrant H19/ IGF2 imprinting in pregnancies conceived by in-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI)
    Author
    Chan Wong, Edgar Antonio
    Place
    Vancouver, BC
    Publisher
    University of British Columbia
    Year Published
    2011
    Topics
    Faculty of Medicine
    Theses
    Abstract
    In-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are two of the most common forms of assisted reproductive technologies (ARTs) used to treat human infertility. Presently, over two million children have been conceived by ART. The majority of these children are born healthy. However, IVF and ICSI have been associated with increased risks of adverse perinatal health outcomes. The higher risk of low birth weight, intrauterine growth restriction, and small for gestational age are of special concern due to its association with adult-onset diseases. In this thesis project, the effect of ART on the genetic and epigenetic status of the placenta, and their associations with fetal growth restriction are examined.
    Language
    English
    Material Type
    Thesis
    Agency
    BC Children's and Women's
    Location
    Study & Learning Commons
    URL
    http://hdl.handle.net/2429/33832
    Audience
    Professional
    Call Number
    Thesis Shelf
    Copy 1 BC Children's and Women's Study & Learning Commons Thesis Shelf Available
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